Product Data Sheet
Aβ42 agonist-1
Catalog No. A78279
Aβ42 agonist-1 is a selective ligand targeting Aβ42, facilitating the aggregation of Aβ42 peptides. This compound interacts with Aβ42 oligomers and pentamers, promoting the self-assembly of nontoxic aggregates and accelerating the formation of fibrils. Additionally, Aβ42 agonist-1 effectively inhibits Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells, making it a valuable tool for research into Alzheimer's disease mechanisms and therapeutic strategies.
Chemical Information
| Catalog Num | A78279 |
|---|---|
| M. Wt | 237.25 |
| Formula | C15H11NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 50635-12-6 |
| Synonyms | |
| SMILES | O=C(C1=CC2=C(C=CC=C2)O1)NC3=CC=CC=C3 |
Biological Activity
| Description | Aβ42 agonist-1 is a selective ligand targeting Aβ42, facilitating the aggregation of Aβ42 peptides. This compound interacts with Aβ42 oligomers and pentamers, promoting the self-assembly of nontoxic aggregates and accelerating the formation of fibrils. Additionally, Aβ42 agonist-1 effectively inhibits Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells, making it a valuable tool for research into Alzheimer's disease mechanisms and therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
