Product Data Sheet

Glimepiride-d5

Catalog No. A78287

main product photo
Glimepiride-d5 is a deuterated derivative of Glimepiride, a medium-to-long acting sulfonylurea antidiabetic agent. This stable isotope is primarily used in pharmacokinetic studies to trace the compound's metabolic pathways and evaluate its biological efficacy. With an ED50 of 182 μg/kg, Glimepiride effectively stimulates insulin secretion from pancreatic beta cells, making it relevant for diabetes research and therapeutic investigations.
Chemical Information
Catalog NumA78287
M. Wt495.65
FormulaC24H29D5N4O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1028809-90-6
Synonyms
SMILESC[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(N3C(C(C([2H])([2H])C([2H])([2H])[2H])=C(C3)C)=O)=O)(=O)=O)=O
Biological Activity
DescriptionGlimepiride-d5 is a deuterated derivative of Glimepiride, a medium-to-long acting sulfonylurea antidiabetic agent. This stable isotope is primarily used in pharmacokinetic studies to trace the compound's metabolic pathways and evaluate its biological efficacy. With an ED50 of 182 μg/kg, Glimepiride effectively stimulates insulin secretion from pancreatic beta cells, making it relevant for diabetes research and therapeutic investigations.
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