Product Data Sheet
Neuroinflammatory-IN-2
Catalog No. A78318
Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent that targets MAO-B with an IC50 value of 10.30 μM. It demonstrates significant inhibition of Aβ1-42 aggregation, achieving 96.33% reduction at a concentration of 25 μM. Additionally, Neuroinflammatory-IN-2 provides neuroprotective effects in H2O2-induced PC-12 cell injury and exhibits biometal chelating and antioxidant properties. With favorable blood-brain barrier permeability, this compound is suitable for research applications related to Alzheimer’s disease and neuroinflammatory conditions.
Chemical Information
| Catalog Num | A78318 |
|---|---|
| M. Wt | 422.49 |
| Formula | C25H27FN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2361384-14-5 |
| Synonyms | |
| SMILES | CC(C1=CC=C(C2=CC=C(NCC3=CC(N(C)C)=CC=C3O)C=C2)C(F)=C1)C(OC)=O |
Biological Activity
| Description | Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent that targets MAO-B with an IC50 value of 10.30 μM. It demonstrates significant inhibition of Aβ1-42 aggregation, achieving 96.33% reduction at a concentration of 25 μM. Additionally, Neuroinflammatory-IN-2 provides neuroprotective effects in H2O2-induced PC-12 cell injury and exhibits biometal chelating and antioxidant properties. With favorable blood-brain barrier permeability, this compound is suitable for research applications related to Alzheimer’s disease and neuroinflammatory conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
