Product Data Sheet

AC 253

Catalog No. A78324

main product photo
AC 253 is an amylin antagonist that specifically inhibits the binding of 125I-adrenomedullin, demonstrating an IC50 value of 25 nM. This compound is valuable for research applications focused on metabolic disorders and neurodegenerative diseases, where modulation of amylin pathways may play a critical role.
Chemical Information
Catalog NumA78324
M. Wt2847.11
FormulaC122H196N40O39
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.151804-79-4
Synonyms
SMILESC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC(C)C)NC(C)=O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCC(N)=O)=O)[C@@H](C)O)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)CO)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC3
Biological Activity
DescriptionAC 253 is an amylin antagonist that specifically inhibits the binding of 125I-adrenomedullin, demonstrating an IC50 value of 25 nM. This compound is valuable for research applications focused on metabolic disorders and neurodegenerative diseases, where modulation of amylin pathways may play a critical role.
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SHIPPING AND STORAGE
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