Product Data Sheet

MeS-IMPY

Catalog No. A78328

main product photo
MeS-IMPY is a selective imaging ligand for β-amyloid plaques, demonstrating high binding affinity to β-amyloid extracted from human brains affected by Alzheimer's disease (AD) with Ki values of 7.93 nM and 8.95 nM for isolated plaques and brain homogenates, respectively. This compound shows promise as a radioligand for positron emission tomography (PET) imaging of β-amyloid plaques, facilitating the evaluation of AD pathology in research applications.
Chemical Information
Catalog NumA78328
M. Wt283.39
FormulaC16H17N3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.955376-42-8
Synonyms
SMILESCSC1=CN2C=C(C3=CC=C(N(C)C)C=C3)N=C2C=C1
Biological Activity
DescriptionMeS-IMPY is a selective imaging ligand for β-amyloid plaques, demonstrating high binding affinity to β-amyloid extracted from human brains affected by Alzheimer's disease (AD) with Ki values of 7.93 nM and 8.95 nM for isolated plaques and brain homogenates, respectively. This compound shows promise as a radioligand for positron emission tomography (PET) imaging of β-amyloid plaques, facilitating the evaluation of AD pathology in research applications.
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