Product Data Sheet
Anti-Aβ agent 1A
Catalog No. A78411
Anti-Aβ Agent 1A is a potent inhibitor of amyloid-β aggregation, contributing to the modulation of neuroinflammatory responses. This compound significantly reduces LPS-induced secretion of pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α, while also decreasing H2O2-induced apoptosis in SH-SY5Y cells via a mitochondrial pathway. With its combined antioxidant, anti-inflammatory, and neuroprotective properties, Anti-Aβ Agent 1A is a valuable tool for research focused on Alzheimer’s disease and related neurodegenerative disorders.
Chemical Information
| Catalog Num | A78411 |
|---|---|
| M. Wt | 547.77 |
| Formula | C35H49NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2313346-53-9 |
| Synonyms | |
| SMILES | C[C@@]12[C@]3([H])[C@](O[C@]4(CC[C@H](CO4)C)[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@@]6(C(C[C@H](CC6)OC(NCC7=CC=CC=C7)=O)=CC5)C)([H])CC2 |
Biological Activity
| Description | Anti-Aβ Agent 1A is a potent inhibitor of amyloid-β aggregation, contributing to the modulation of neuroinflammatory responses. This compound significantly reduces LPS-induced secretion of pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α, while also decreasing H2O2-induced apoptosis in SH-SY5Y cells via a mitochondrial pathway. With its combined antioxidant, anti-inflammatory, and neuroprotective properties, Anti-Aβ Agent 1A is a valuable tool for research focused on Alzheimer’s disease and related neurodegenerative disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
