Product Data Sheet

(Glu20)-Amyloid β-Protein (1-42)

Catalog No. A78440

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(Glu20)-Amyloid β-Protein (1-42) is a modified variant of amyloid β-protein designed to reduce the aggregation propensity associated with Aβ42. The Glu20 mutation results in a slower fibrillization process, thereby preventing the accumulation of this peptide. This compound holds significant relevance for research into the pathophysiology of Alzheimer's disease, where amyloid β-protein is a key component of amyloid deposits in both vascular and parenchymal tissues.
Chemical Information
Catalog NumA78440
M. Wt4495.98
FormulaC199H309N55O62S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1802086-22-1
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Biological Activity
Description(Glu20)-Amyloid β-Protein (1-42) is a modified variant of amyloid β-protein designed to reduce the aggregation propensity associated with Aβ42. The Glu20 mutation results in a slower fibrillization process, thereby preventing the accumulation of this peptide. This compound holds significant relevance for research into the pathophysiology of Alzheimer's disease, where amyloid β-protein is a key component of amyloid deposits in both vascular and parenchymal tissues.
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