Product Data Sheet
β-Secretase substrate VI, fluorogenic
Catalog No. A78495
β-Secretase substrate VI, fluorogenic is a fluorogenic peptide labeled with EDANS and DABCYL, specifically designed for the measurement of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) activity. This substrate enables the quantification of BACE1 enzymatic activity through fluorescence emission (Em=360nm, Ex=528nm), providing a direct correlation between enzyme activity levels and fluorescence intensity. It is an essential tool for researchers studying Alzheimer's disease and related amyloidogenic processes.
Chemical Information
| Catalog Num | A78495 |
|---|---|
| M. Wt | 2005.22 |
| Formula | C91H129N25O25S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 310427-94-2 |
| Synonyms | RE(EDANS)EVNLDAEFK(DABCYL)R |
| SMILES | N(CCNC(CC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCCNC(=O)C2=CC=C(N=NC3=CC=C(N(C)C)C=C3)C=C2)=O)=O)CCC(O)=O)=O)C)=O)CC(O)=O)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)CCC(O)=O)=O)NC([C@H](CCCNC(=N)N)N)=O)=O)C=4C5=C(C(S(=O)(=O)O)=CC=C5)C=CC4 |
Biological Activity
| Description | β-Secretase substrate VI, fluorogenic is a fluorogenic peptide labeled with EDANS and DABCYL, specifically designed for the measurement of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) activity. This substrate enables the quantification of BACE1 enzymatic activity through fluorescence emission (Em=360nm, Ex=528nm), providing a direct correlation between enzyme activity levels and fluorescence intensity. It is an essential tool for researchers studying Alzheimer's disease and related amyloidogenic processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
