Mevalonolactone
Catalog No. A78504

Mevalonolactone is a sesquiterpene lactone that acts as a calcineurin inhibitor, demonstrating inhibitory activity with an IC50 value of 134.29 μM against p-Nitrophenyl phosphate. This compound is primarily used in research exploring cellular signaling pathways, immune response modulation, and potential therapeutic applications for disorders involving calcineurin activity. Its ability to inhibit calcineurin makes it valuable for investigations into T cell activation and cytokine production.
Chemical Information
| Catalog Num | A78504 |
|---|---|
| M. Wt | 130.14 |
| Formula | C6H10O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19115-49-2 |
| Synonyms | |
| SMILES | O=C1C[C@](C)(O)CCO1 |
Biological Activity
| Description | Mevalonolactone is a sesquiterpene lactone that acts as a calcineurin inhibitor, demonstrating inhibitory activity with an IC50 value of 134.29 μM against p-Nitrophenyl phosphate. This compound is primarily used in research exploring cellular signaling pathways, immune response modulation, and potential therapeutic applications for disorders involving calcineurin activity. Its ability to inhibit calcineurin makes it valuable for investigations into T cell activation and cytokine production. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


