Product Data Sheet

ACG548B

Catalog No. A78558

main product photo
ACG548B is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 1.78 µM and 0.496 µM, respectively. It exhibits strong affinity and selectivity for AChE over BChE and choline kinase (ChoK). ACG548B is suitable for research applications focused on myasthenia gravis and the mechanisms of neuromuscular blockade.
Chemical Information
Catalog NumA78558
M. Wt777.42
FormulaC38H34Br2Cl2N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.795316-16-4
Synonyms
SMILESCN(C1=CC=[N+](CC2=CC(C3=CC=CC(C[N+]4=CC=C(N(C5=CC=C(Cl)C=C5)C)C=C4)=C3)=CC=C2)C=C1)C6=CC=C(Cl)C=C6.[Br-].[Br-]
Biological Activity
DescriptionACG548B is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 1.78 µM and 0.496 µM, respectively. It exhibits strong affinity and selectivity for AChE over BChE and choline kinase (ChoK). ACG548B is suitable for research applications focused on myasthenia gravis and the mechanisms of neuromuscular blockade.
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