4-Methoxyphenyl isothiocyanate
Catalog No. A78594

4-Methoxyphenyl isothiocyanate primarily acts as an antioxidant, demonstrating a notable IC50 value of 1.25 mM for the scavenging of DPPH radicals. It displays significant antioxidant capacity, equivalent to 11.7 mM TE based on ORAC testing, and prolongs oxidation in the Briggs–Rauscher reaction by approximately 9180 seconds. In addition to its antioxidant properties, 4-Methoxyphenyl isothiocyanate exhibits moderate inhibitory activity against cholinesterases, with 30.4% inhibition of acetylcholinesterase and 17.9% inhibition of butyrylcholinesterase. This compound is valuable for research in antioxidative mechanisms and potential applications in addressing neurological disorders.
Chemical Information
| Catalog Num | A78594 |
|---|---|
| M. Wt | 165.21 |
| Formula | C8H7NOS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2284-20-0 |
| Synonyms | 4-Methylphenyl ITC |
| SMILES | COC1=CC=C(N=C=S)C=C1 |
Biological Activity
| Description | 4-Methoxyphenyl isothiocyanate primarily acts as an antioxidant, demonstrating a notable IC50 value of 1.25 mM for the scavenging of DPPH radicals. It displays significant antioxidant capacity, equivalent to 11.7 mM TE based on ORAC testing, and prolongs oxidation in the Briggs–Rauscher reaction by approximately 9180 seconds. In addition to its antioxidant properties, 4-Methoxyphenyl isothiocyanate exhibits moderate inhibitory activity against cholinesterases, with 30.4% inhibition of acetylcholinesterase and 17.9% inhibition of butyrylcholinesterase. This compound is valuable for research in antioxidative mechanisms and potential applications in addressing neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


