Product Data Sheet

Donepezil-d7 hydrochloride

Catalog No. A78597

main product photo
Donepezil-d7 hydrochloride is a deuterium-labeled variant of Donepezil, a potent inhibitor of acetylcholinesterase (AChE). This compound exhibits specific inhibition with IC50 values of 8.12 nM for bovine AChE and 11.6 nM for human AChE. Donepezil-d7 hydrochloride is primarily used in chemical research to trace the metabolism and pharmacokinetics of Donepezil in various biological systems.
Chemical Information
Catalog NumA78597
M. Wt423.00
FormulaC24H23D7ClNO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1261394-20-0
SynonymsE2020-d7
SMILESO=C1C2=CC(OC)=C(OC)C=C2CC1CC3CCN(CC3)C([2H])([2H])C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H].Cl
Biological Activity
DescriptionDonepezil-d7 hydrochloride is a deuterium-labeled variant of Donepezil, a potent inhibitor of acetylcholinesterase (AChE). This compound exhibits specific inhibition with IC50 values of 8.12 nM for bovine AChE and 11.6 nM for human AChE. Donepezil-d7 hydrochloride is primarily used in chemical research to trace the metabolism and pharmacokinetics of Donepezil in various biological systems.
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