Product Data Sheet
Velnacrine
Catalog No. A78622
Velnacrine is a potent inhibitor of acetylcholinesterase (AChE), displaying an IC50 of 3.27 μM. This compound has demonstrated the ability to reverse scopolamine-induced amnesia in rat models, highlighting its potential in cognitive research. Additionally, Velnacrine exhibits acute toxicity with an LD50 of 65 mg/kg, warranting careful handling during experimental applications.
Chemical Information
| Catalog Num | A78622 |
|---|---|
| M. Wt | 214.26 |
| Formula | C13H14N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 124027-47-0 |
| Synonyms | HP 029 free base; Hydroxytacrine |
| SMILES | OC1CCCC2=NC3=CC=CC=C3C(N)=C21 |
Biological Activity
| Description | Velnacrine is a potent inhibitor of acetylcholinesterase (AChE), displaying an IC50 of 3.27 μM. This compound has demonstrated the ability to reverse scopolamine-induced amnesia in rat models, highlighting its potential in cognitive research. Additionally, Velnacrine exhibits acute toxicity with an LD50 of 65 mg/kg, warranting careful handling during experimental applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
