Z32439948
Catalog No. A78628

Z32439948 is a butyrylcholinesterase (BChE) inhibitor with an IC50 of 1.4 μM against human BChE. This compound, a derivative of m-sulfamoylbenzamide, demonstrates neuroprotective properties, particularly against glutamate-induced toxicity in SH-SY5Y neuronal cell lines. Z32439948 is valuable for research in neurodegenerative disease models and therapeutic strategies targeting cholinergic dysfunction.
Chemical Information
| Catalog Num | A78628 |
|---|---|
| M. Wt | 478.56 |
| Formula | C25H26N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 920845-86-9 |
| Synonyms | |
| SMILES | O=C(NCCC1=CNC2=C1C=CC=C2)C3=CC=C(OC)C(S(NCCC4=NC=CC=C4)(=O)=O)=C3 |
Biological Activity
| Description | Z32439948 is a butyrylcholinesterase (BChE) inhibitor with an IC50 of 1.4 μM against human BChE. This compound, a derivative of m-sulfamoylbenzamide, demonstrates neuroprotective properties, particularly against glutamate-induced toxicity in SH-SY5Y neuronal cell lines. Z32439948 is valuable for research in neurodegenerative disease models and therapeutic strategies targeting cholinergic dysfunction. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


