Product Data Sheet
Xanthohumol I
Catalog No. A78675
Xanthohumol I is a chalcone derivative of Xanthohumol, known for its role as a Cholinesterase (ChE) inhibitor. It effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 71.34 μM and 32.67 μM, respectively. Additionally, its hydroxy derivative, 3-hydroxy-xanthohumol, also demonstrates inhibitory effects on AChE and BChE, with IC50 values of 51.25 μM and 63.07 μM. This compound is valuable for research in neurodegenerative diseases and related biochemical pathways.
Chemical Information
| Catalog Num | A78675 |
|---|---|
| M. Wt | 370.40 |
| Formula | C21H22O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 688360-06-7 |
| Synonyms | |
| SMILES | OC1=CC=C(/C=C/C(C2=C3OC(C(C)(O)C)CC3=C(O)C=C2OC)=O)C=C1 |
Biological Activity
| Description | Xanthohumol I is a chalcone derivative of Xanthohumol, known for its role as a Cholinesterase (ChE) inhibitor. It effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 71.34 μM and 32.67 μM, respectively. Additionally, its hydroxy derivative, 3-hydroxy-xanthohumol, also demonstrates inhibitory effects on AChE and BChE, with IC50 values of 51.25 μM and 63.07 μM. This compound is valuable for research in neurodegenerative diseases and related biochemical pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
