Product Data Sheet
Ambenonium dichloride tetrahydrate
Catalog No. A78685
Ambenonium dichloride tetrahydrate is a potent, orally active, reversible inhibitor of acetylcholinesterase (AChE). This compound demonstrates a high affinity for human AChE, with an IC50 value of 0.7 nM, making it valuable for investigations into cholinergic system modulation. Its primary applications include the study of neurodegenerative diseases such as myasthenia gravis and Alzheimer's disease, as well as broader neuropharmacological research.
Chemical Information
| Catalog Num | A78685 |
|---|---|
| M. Wt | 680.53 |
| Formula | C28H50Cl4N4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 52022-31-8 |
| Synonyms | WIN 8077 dichloride tetrahydrate |
| SMILES | O=C(NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)C(NCC[N+](CC)(CC)CC2=CC=CC=C2Cl)=O.[Cl-].[Cl-].O.O.O.O |
Biological Activity
| Description | Ambenonium dichloride tetrahydrate is a potent, orally active, reversible inhibitor of acetylcholinesterase (AChE). This compound demonstrates a high affinity for human AChE, with an IC50 value of 0.7 nM, making it valuable for investigations into cholinergic system modulation. Its primary applications include the study of neurodegenerative diseases such as myasthenia gravis and Alzheimer's disease, as well as broader neuropharmacological research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
