Product Data Sheet
AChE/BChE-IN-6
Catalog No. A78740
AChE/BChE-IN-6 is a potent dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting IC50 values of 0.809 µM for AChE and 2.248 µM for BChE, with limited activity against hMAO-B. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for research focused on Alzheimer's disease. Its ability to inhibit cholinesterases suggests potential applications in studies aiming to understand and develop treatments for neurodegenerative conditions characterized by cholinergic dysfunction.
Chemical Information
| Catalog Num | A78740 |
|---|---|
| M. Wt | 366.50 |
| Formula | C23H30N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2416910-94-4 |
| Synonyms | |
| SMILES | CC(C1=CC=C(C=C1)NC(OCC2CCN(CC2)CC3=CC=CC=C3)=O)C |
Biological Activity
| Description | AChE/BChE-IN-6 is a potent dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting IC50 values of 0.809 µM for AChE and 2.248 µM for BChE, with limited activity against hMAO-B. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for research focused on Alzheimer's disease. Its ability to inhibit cholinesterases suggests potential applications in studies aiming to understand and develop treatments for neurodegenerative conditions characterized by cholinergic dysfunction. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
