Product Data Sheet

Quilostigmine

Catalog No. A78763

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Quilostigmine is a potent acetylcholinesterase inhibitor with an IC50 of 148 nM in rat brain acetylcholinesterase. This orally active analogue of Physostigmine demonstrates prolonged efficacy in reducing tremors. Its mechanism of action makes it a valuable tool for research related to Alzheimer's disease and other cognitive disorders.
Chemical Information
Catalog NumA78763
M. Wt377.48
FormulaC23H27N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.139314-01-5
SynonymsHP-290; NXX-066
SMILESO=C(N1CC2=C(C=CC=C2)CC1)OC3=CC4=C(N(C)[C@]5([H])[C@@]4(C)CCN5C)C=C3
Biological Activity
DescriptionQuilostigmine is a potent acetylcholinesterase inhibitor with an IC50 of 148 nM in rat brain acetylcholinesterase. This orally active analogue of Physostigmine demonstrates prolonged efficacy in reducing tremors. Its mechanism of action makes it a valuable tool for research related to Alzheimer's disease and other cognitive disorders.
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