Product Data Sheet
Dihydro Donepezil
Catalog No. A78771
Dihydro Donepezil is a potent cholinesterase (ChE) inhibitor, serving as a metabolite of Donepezil. It demonstrates significant biological activity, inhibiting acetylcholinesterase with IC50 values of 8.12 nM for bovine acetylcholinesterase (bAChE) and 11.6 nM for human acetylcholinesterase (hAChE). This compound is primarily utilized in research focused on neurodegenerative disorders and cognitive enhancement, contributing to studies on Alzheimer's disease and related pathways.
Chemical Information
| Catalog Num | A78771 |
|---|---|
| M. Wt | 381.51 |
| Formula | C24H31NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 120012-04-6 |
| Synonyms | Dihydro E2020 |
| SMILES | OC1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4 |
Biological Activity
| Description | Dihydro Donepezil is a potent cholinesterase (ChE) inhibitor, serving as a metabolite of Donepezil. It demonstrates significant biological activity, inhibiting acetylcholinesterase with IC50 values of 8.12 nM for bovine acetylcholinesterase (bAChE) and 11.6 nM for human acetylcholinesterase (hAChE). This compound is primarily utilized in research focused on neurodegenerative disorders and cognitive enhancement, contributing to studies on Alzheimer's disease and related pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
