AChE/BChE-IN-3 hydrochloride
Catalog No. A78778

AChE/BChE-IN-3 hydrochloride is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting IC50 values of 6.08 μM against electric eel AChE and 0.383 μM against equine serum BChE. This compound is valuable for research focused on neurodegenerative diseases and cholinergic dysfunction, providing insights into the modulation of cholinergic signaling pathways. Its potent inhibitory effects make it a useful tool for studying enzyme kinetics and drug discovery related to cognitive decline.
Chemical Information
| Catalog Num | A78778 |
|---|---|
| M. Wt | 316.82 |
| Formula | C15H25ClN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2410992-69-5 |
| Synonyms | |
| SMILES | O=C(OC1=CC=CC(C(O)CNC(C)(C)C)=C1)N(C)C.[H]Cl |
Biological Activity
| Description | AChE/BChE-IN-3 hydrochloride is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting IC50 values of 6.08 μM against electric eel AChE and 0.383 μM against equine serum BChE. This compound is valuable for research focused on neurodegenerative diseases and cholinergic dysfunction, providing insights into the modulation of cholinergic signaling pathways. Its potent inhibitory effects make it a useful tool for studying enzyme kinetics and drug discovery related to cognitive decline. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


