Product Data Sheet
Monardic acid A
Catalog No. A78791
Monardic acid A is a selective inhibitor of acetylcholinesterase (AChE), exhibiting an IC50 of 53.1 μM against AChE from electric eel. It displays weak inhibitory activity against human erythrocyte AChE (IC50 >100 μM) and negligible effects on butyrylcholinesterase (BChE). By inhibiting AChE activity, Monardic acid A effectively reduces acetylcholine breakdown, contributing to its anti-inflammatory properties and modulation of neurotransmitter release. This compound is sourced from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), making it valuable for research in anti-inflammatory drug development and neurodegenerative disease therapeutics.
Chemical Information
| Catalog Num | A78791 |
|---|---|
| M. Wt | 538.46 |
| Formula | C27H22O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1607436-76-9 |
| Synonyms | |
| SMILES | OC([C@@H]1C2=C(/C=C/C(O[C@@H](C(O)=O)CC3=CC(O)=C(C=C3)O)=O)C=CC(O)=C2O[C@H]1C4=CC(O)=C(C=C4)O)=O |
Biological Activity
| Description | Monardic acid A is a selective inhibitor of acetylcholinesterase (AChE), exhibiting an IC50 of 53.1 μM against AChE from electric eel. It displays weak inhibitory activity against human erythrocyte AChE (IC50 >100 μM) and negligible effects on butyrylcholinesterase (BChE). By inhibiting AChE activity, Monardic acid A effectively reduces acetylcholine breakdown, contributing to its anti-inflammatory properties and modulation of neurotransmitter release. This compound is sourced from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus), making it valuable for research in anti-inflammatory drug development and neurodegenerative disease therapeutics. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
