Product Data Sheet
AChE-IN-41
Catalog No. A78814
AChE-IN-41 is a cholinesterase inhibitor designed to enhance acetylcholine levels by preventing its breakdown. This hybrid compound of Galantamine and Memantine demonstrates significant inhibition of cholinesterase activity, offering valuable insights for neurological research. AChE-IN-41 exhibits enhanced plasma stability and similar microsomal stability in vitro, although it possesses a shorter half-life and faster clearance in vivo, making it suitable for studies on cholinergic signaling and potential therapeutic applications in neurodegenerative diseases.
Chemical Information
| Catalog Num | A78814 |
|---|---|
| M. Wt | 504.70 |
| Formula | C32H44N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3038811-77-4 |
| Synonyms | |
| SMILES | O[C@H]1C=C[C@@]23C(C(CN(C/C=C/CN[C@@]45C[C@]6(C)C[C@@](C5)(C)C[C@@H](C6)C4)CC3)=CC=C7OC)=C7O[C@H]2C1 |
Biological Activity
| Description | AChE-IN-41 is a cholinesterase inhibitor designed to enhance acetylcholine levels by preventing its breakdown. This hybrid compound of Galantamine and Memantine demonstrates significant inhibition of cholinesterase activity, offering valuable insights for neurological research. AChE-IN-41 exhibits enhanced plasma stability and similar microsomal stability in vitro, although it possesses a shorter half-life and faster clearance in vivo, making it suitable for studies on cholinergic signaling and potential therapeutic applications in neurodegenerative diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
