Product Data Sheet
VU0366369
Catalog No. A78837
VU0366369 is a selective positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor subtype M1, exhibiting an EC50 value of 830 nM. This compound has demonstrated potential for enhancing M1 receptor function, making it a valuable tool in the study of central nervous system disorders. Researchers may utilize VU0366369 to explore therapeutic strategies for conditions such as Alzheimer's disease and schizophrenia, focusing on cholinergic signaling pathways.
Chemical Information
| Catalog Num | A78837 |
|---|---|
| M. Wt | 335.33 |
| Formula | C19H14FN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1222834-53-8 |
| Synonyms | ML137 |
| SMILES | O=C1C(N(CC2=C(F)C=C(C3=CN(C)N=C3)C=C2)C4=C1C=CC=C4)=O |
Biological Activity
| Description | VU0366369 is a selective positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor subtype M1, exhibiting an EC50 value of 830 nM. This compound has demonstrated potential for enhancing M1 receptor function, making it a valuable tool in the study of central nervous system disorders. Researchers may utilize VU0366369 to explore therapeutic strategies for conditions such as Alzheimer's disease and schizophrenia, focusing on cholinergic signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
