Product Data Sheet
RS 45041-190 hydrochloride
Catalog No. A78965
RS 45041-190 hydrochloride is a high-affinity ligand for I2 imidazoline receptors, exhibiting pKis of 8.66, 9.37, 9.32, and 8.85 in kidney tissues from rat, rabbit, dog, and baboon, respectively. This compound demonstrates moderate inhibitory activity against monoamine oxidase A with a pIC50 of 6.12, while its potency against monoamine oxidase B is lower, with a pIC50 of 4.47. RS 45041-190 hydrochloride is useful in studying the role of imidazoline receptors and the modulation of monoamine oxidase activity in various biological contexts.
Chemical Information
| Catalog Num | A78965 |
|---|---|
| M. Wt | 258.15 |
| Formula | C11H13Cl2N3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 204274-74-8 |
| Synonyms | |
| SMILES | ClC1=CC=CC2=C1CN(C3=NCCN3)C2.Cl |
Biological Activity
| Description | RS 45041-190 hydrochloride is a high-affinity ligand for I2 imidazoline receptors, exhibiting pKis of 8.66, 9.37, 9.32, and 8.85 in kidney tissues from rat, rabbit, dog, and baboon, respectively. This compound demonstrates moderate inhibitory activity against monoamine oxidase A with a pIC50 of 6.12, while its potency against monoamine oxidase B is lower, with a pIC50 of 4.47. RS 45041-190 hydrochloride is useful in studying the role of imidazoline receptors and the modulation of monoamine oxidase activity in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
