Product Data Sheet
PSB-1491
Catalog No. A79033
PSB-1491 is a selective and competitive inhibitor of monoamine oxidase B (MAO-B), demonstrating an IC50 value of 0.386 nM for human MAO-B. This compound exhibits over 25,000-fold selectivity towards MAO-B compared to MAO-A, making it a valuable tool for studying neurodegenerative diseases and exploring potential therapeutic applications in disorders such as Parkinson's disease. Its high potency and selectivity make PSB-1491 an important reagent for research focused on modulating monoamine neurotransmitter levels.
Chemical Information
| Catalog Num | A79033 |
|---|---|
| M. Wt | 320.17 |
| Formula | C15H11Cl2N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1619884-67-1 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(C(Cl)=C1)Cl)C2=CC3=C(C=C2)N(N=C3)C |
Biological Activity
| Description | PSB-1491 is a selective and competitive inhibitor of monoamine oxidase B (MAO-B), demonstrating an IC50 value of 0.386 nM for human MAO-B. This compound exhibits over 25,000-fold selectivity towards MAO-B compared to MAO-A, making it a valuable tool for studying neurodegenerative diseases and exploring potential therapeutic applications in disorders such as Parkinson's disease. Its high potency and selectivity make PSB-1491 an important reagent for research focused on modulating monoamine neurotransmitter levels. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
