Product Data Sheet
hMAO-B-IN-2
Catalog No. A79038
hMAO-B-IN-2 is a potent and selective inhibitor of human monoamine oxidase B (hMAO-B), exhibiting a competitive reversible mechanism with an IC50 of 4 nM. This compound is characterized by its ability to penetrate the blood-brain barrier and demonstrates low toxicity alongside significant neuroprotective effects in SH-SY5Y neuroblastoma cells. hMAO-B-IN-2 is suitable for research applications related to Alzheimer's disease and also serves as a versatile click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
Chemical Information
| Catalog Num | A79038 |
|---|---|
| M. Wt | 301.38 |
| Formula | C18H23NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2454459-87-9 |
| Synonyms | |
| SMILES | C#CCN(CCCCCOC1=CC2=C(C(CCO2)=O)C=C1)C |
Biological Activity
| Description | hMAO-B-IN-2 is a potent and selective inhibitor of human monoamine oxidase B (hMAO-B), exhibiting a competitive reversible mechanism with an IC50 of 4 nM. This compound is characterized by its ability to penetrate the blood-brain barrier and demonstrates low toxicity alongside significant neuroprotective effects in SH-SY5Y neuroblastoma cells. hMAO-B-IN-2 is suitable for research applications related to Alzheimer's disease and also serves as a versatile click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
