Product Data Sheet
MAO-B-IN-44
Catalog No. A79082
MAO-B-IN-44 is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting an IC50 value of 1.01 μM while showing minimal inhibition of MAO-A (IC50 = 14.4 μM). This compound effectively reduces the degradation of neurotransmitters, particularly dopamine, making it a valuable tool for studying neurodegenerative disorders linked to MAO-B dysregulation, such as Parkinson's disease. Its selective inhibition can aid in understanding the role of MAO-B in neural pathophysiology and contribute to the development of targeted therapies.
Chemical Information
| Catalog Num | A79082 |
|---|---|
| M. Wt | 624.64 |
| Formula | C34H32N4O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1454707-25-5 |
| Synonyms | |
| SMILES | O=C(C1=C(NC2=CC=C(OC)C=C2)CC(C3=CC=C([N+]([O-])=O)C=C3)N(C4=CC=C(OC)C=C4)C1C5=CC=C([N+]([O-])=O)C=C5)OCC |
Biological Activity
| Description | MAO-B-IN-44 is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting an IC50 value of 1.01 μM while showing minimal inhibition of MAO-A (IC50 = 14.4 μM). This compound effectively reduces the degradation of neurotransmitters, particularly dopamine, making it a valuable tool for studying neurodegenerative disorders linked to MAO-B dysregulation, such as Parkinson's disease. Its selective inhibition can aid in understanding the role of MAO-B in neural pathophysiology and contribute to the development of targeted therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
