Product Data Sheet
Selegiline-d5 hydrochloride
Catalog No. A79118
Selegiline-d5 hydrochloride is a deuterium-labeled form of the irreversible monoamine oxidase B (MAO-B) inhibitor, Selegiline. This compound exhibits a high selectivity for MAO-B with an IC50 of 51 nM, demonstrating 450-fold preference over MAO-A (IC50 = 23 μM). Selegiline-d5 hydrochloride is utilized in research related to neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and major depressive disorder, providing valuable insights into the biochemical pathways involved in these conditions.
Chemical Information
| Catalog Num | A79118 |
|---|---|
| M. Wt | 228.77 |
| Formula | C13H13D5ClN |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217705-21-9 |
| Synonyms | Deprenyl-d5 hydrochloride; (-)-Selegiline-d5 hydrochloride; (-)-Deprenyl-d5 hydrochloride |
| SMILES | C#CCN(C)[C@H](C)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H].Cl |
Biological Activity
| Description | Selegiline-d5 hydrochloride is a deuterium-labeled form of the irreversible monoamine oxidase B (MAO-B) inhibitor, Selegiline. This compound exhibits a high selectivity for MAO-B with an IC50 of 51 nM, demonstrating 450-fold preference over MAO-A (IC50 = 23 μM). Selegiline-d5 hydrochloride is utilized in research related to neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and major depressive disorder, providing valuable insights into the biochemical pathways involved in these conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
