Product Data Sheet
NADI-351
Catalog No. A79147
NADI-351 is a potent orally active inhibitor of Notch1, specifically designed to disrupt Notch1 transcription complexes and decrease its recruitment to target genes. This compound exhibits significant efficacy in inhibiting Notch1 signaling pathways, making it a valuable tool for cancer research. Its selective action provides insights into the role of Notch1 in tumorigenesis and related cellular processes.
Chemical Information
| Catalog Num | A79147 |
|---|---|
| M. Wt | 465.52 |
| Formula | C19H20FN5O4S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2503017-11-4 |
| Synonyms | |
| SMILES | C/C(C1=CC(OC)=C(C(F)=C1)OCC2=NN=CN2)=C3C(N(C(S\3)=S)CC(N(C)C)=O)=O |
Biological Activity
| Description | NADI-351 is a potent orally active inhibitor of Notch1, specifically designed to disrupt Notch1 transcription complexes and decrease its recruitment to target genes. This compound exhibits significant efficacy in inhibiting Notch1 signaling pathways, making it a valuable tool for cancer research. Its selective action provides insights into the role of Notch1 in tumorigenesis and related cellular processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
