Product Data Sheet

Glemanserin

Catalog No. A79188

main product photo
Glemanserin is a potent and selective antagonist for the serotonin receptor 5-HT2A, exhibiting nanomolar affinity in various species (Ki values of 2.89, 0.54, and 2.5 nM for rat, rabbit, and human 5-HT2A, respectively). This compound is primarily utilized in neuropharmacological research to study the role of 5-HT2A receptors in various physiological and pathological conditions. Its antagonistic activity contributes to investigations into mood disorders, anxiety, and other CNS-related ailments.
Chemical Information
Catalog NumA79188
M. Wt295.42
FormulaC20H25NO
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.107703-78-6
SynonymsMDL11939
SMILESOC(C1=CC=CC=C1)C2CCN(CCC3=CC=CC=C3)CC2
Biological Activity
DescriptionGlemanserin is a potent and selective antagonist for the serotonin receptor 5-HT2A, exhibiting nanomolar affinity in various species (Ki values of 2.89, 0.54, and 2.5 nM for rat, rabbit, and human 5-HT2A, respectively). This compound is primarily utilized in neuropharmacological research to study the role of 5-HT2A receptors in various physiological and pathological conditions. Its antagonistic activity contributes to investigations into mood disorders, anxiety, and other CNS-related ailments.
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