Clomipramine-d6 hydrochloride
Catalog No. A79209

Clomipramine-d6 hydrochloride is a deuterated form of Clomipramine hydrochloride, primarily acting as a potent inhibitor of serotonin (5-HT) reuptake, with an IC50 value of 1.5 nM. This stable isotope is valuable for research applications in depression and obsessive-compulsive disorder (OCD). Its deuterated nature enables precise quantification and tracing in metabolic studies, facilitating a better understanding of these psychiatric conditions and the pharmacodynamics of tricyclic antidepressants.
Chemical Information
| Catalog Num | A79209 |
|---|---|
| M. Wt | 357.35 |
| Formula | C19H18D6Cl2N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189882-28-7 |
| Synonyms | Chlorimipramine-d6 hydrochloride; G-34586-d6 hydrochloride; NSC-169865-d6 hydrochloride |
| SMILES | [2H]C([2H])([2H])N(C([2H])([2H])[2H])CCCN1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31.Cl[H] |
Biological Activity
| Description | Clomipramine-d6 hydrochloride is a deuterated form of Clomipramine hydrochloride, primarily acting as a potent inhibitor of serotonin (5-HT) reuptake, with an IC50 value of 1.5 nM. This stable isotope is valuable for research applications in depression and obsessive-compulsive disorder (OCD). Its deuterated nature enables precise quantification and tracing in metabolic studies, facilitating a better understanding of these psychiatric conditions and the pharmacodynamics of tricyclic antidepressants. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


