Product Data Sheet
Desvenlafaxine-d10
Catalog No. A79230
Desvenlafaxine-d10 is a deuterated version of Desvenlafaxine, which is the active metabolite of Venlafaxine. It functions primarily as a selective inhibitor of the serotonin and norepinephrine transporters (5-HT and NET), demonstrating IC50 values of 47.3 nM and 531.3 nM, respectively. This compound is utilized in pharmacokinetic studies and research involving neurotransmitter systems, given its ability to penetrate the blood-brain barrier and its limited interaction with the dopamine transporter, where it exhibits only weak inhibitory activity.
Chemical Information
| Catalog Num | A79230 |
|---|---|
| M. Wt | 273.44 |
| Formula | C16H15D10NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1062607-49-1 |
| Synonyms | |
| SMILES | CN(C)CC(C1=CC=C(C=C1)O)C2(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C2([2H])[2H])O |
Biological Activity
| Description | Desvenlafaxine-d10 is a deuterated version of Desvenlafaxine, which is the active metabolite of Venlafaxine. It functions primarily as a selective inhibitor of the serotonin and norepinephrine transporters (5-HT and NET), demonstrating IC50 values of 47.3 nM and 531.3 nM, respectively. This compound is utilized in pharmacokinetic studies and research involving neurotransmitter systems, given its ability to penetrate the blood-brain barrier and its limited interaction with the dopamine transporter, where it exhibits only weak inhibitory activity. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
