Product Data Sheet
Desvenlafaxine-d6
Catalog No. A79236
Desvenlafaxine-d6 is a deuterium-labeled derivative of Desvenlafaxine, which acts as a selective serotonin (5-HT) and norepinephrine reuptake inhibitor. It exhibits significant potency with IC50 values of 47.3 nM for the human serotonin transporter (hSERT) and 531.3 nM for the human norepinephrine transporter (hNET). Additionally, Desvenlafaxine shows minimal binding affinity at the human dopamine transporter, indicating its focused mechanism of action. This stable isotope is valuable for pharmacokinetic studies and metabolic profiling in neuropharmacology research.
Chemical Information
| Catalog Num | A79236 |
|---|---|
| M. Wt | 269.41 |
| Formula | C16H19D6NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1062605-69-9 |
| Synonyms | |
| SMILES | [2H]C([2H])([2H])N(C([2H])([2H])[2H])CC(C1=CC=C(C=C1)O)C2(CCCCC2)O |
Biological Activity
| Description | Desvenlafaxine-d6 is a deuterium-labeled derivative of Desvenlafaxine, which acts as a selective serotonin (5-HT) and norepinephrine reuptake inhibitor. It exhibits significant potency with IC50 values of 47.3 nM for the human serotonin transporter (hSERT) and 531.3 nM for the human norepinephrine transporter (hNET). Additionally, Desvenlafaxine shows minimal binding affinity at the human dopamine transporter, indicating its focused mechanism of action. This stable isotope is valuable for pharmacokinetic studies and metabolic profiling in neuropharmacology research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
