Product Data Sheet
Desvenlafaxine succinate
Catalog No. A79241
Desvenlafaxine succinate is the succinate salt form of the primary active metabolite of Venlafaxine, serving as a selective inhibitor of serotonin and norepinephrine reuptake. It exhibits IC50 values of 47.3 nM for the human serotonin transporter (hSERT) and 531.3 nM for the human norepinephrine transporter (hNET), offering significant potential in modulating neurotransmitter levels. Additionally, Desvenlafaxine succinate demonstrates modest binding affinity at the human dopamine transporter, with 62% inhibition observed at a concentration of 100 μM. This compound is valuable for research in neuropsychiatric conditions and the study of antidepressant mechanisms.
Chemical Information
| Catalog Num | A79241 |
|---|---|
| M. Wt | 381.46 |
| Formula | C20H31NO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 448904-47-0 |
| Synonyms | O-Desmethylvenlafaxine succinate; Wy-45233 succinate |
| SMILES | O=C(O)CCC(O)=O.OC1=CC=C(C(C2(O)CCCCC2)CN(C)C)C=C1 |
Biological Activity
| Description | Desvenlafaxine succinate is the succinate salt form of the primary active metabolite of Venlafaxine, serving as a selective inhibitor of serotonin and norepinephrine reuptake. It exhibits IC50 values of 47.3 nM for the human serotonin transporter (hSERT) and 531.3 nM for the human norepinephrine transporter (hNET), offering significant potential in modulating neurotransmitter levels. Additionally, Desvenlafaxine succinate demonstrates modest binding affinity at the human dopamine transporter, with 62% inhibition observed at a concentration of 100 μM. This compound is valuable for research in neuropsychiatric conditions and the study of antidepressant mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
