Product Data Sheet
Imipramine-d6
Catalog No. A79249
Imipramine-d6 is the deuterium-labeled form of Imipramine hydrochloride, a tricyclic antidepressant that primarily acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. It exhibits notable antitumor activity as a Fascin1 inhibitor, promoting autophagy in U-87MG glioma cells and inducing apoptosis in HL-60 cells. Additionally, Imipramine-d6 demonstrates neuroprotective and immunomodulatory effects, making it valuable for research into depression, cancer, and neurodegenerative disorders.
Chemical Information
| Catalog Num | A79249 |
|---|---|
| M. Wt | 286.44 |
| Formula | C19H18D6N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 65100-45-0 |
| Synonyms | |
| SMILES | C(CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])N1C=2C(CCC=3C1=CC=CC3)=CC=CC2 |
Biological Activity
| Description | Imipramine-d6 is the deuterium-labeled form of Imipramine hydrochloride, a tricyclic antidepressant that primarily acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. It exhibits notable antitumor activity as a Fascin1 inhibitor, promoting autophagy in U-87MG glioma cells and inducing apoptosis in HL-60 cells. Additionally, Imipramine-d6 demonstrates neuroprotective and immunomodulatory effects, making it valuable for research into depression, cancer, and neurodegenerative disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
