Product Data Sheet
AB21 hydrochloride
Catalog No. A79279
AB21 hydrochloride is a potent and selective antagonist of the sigma-1 receptor (S1R), exhibiting a Ki of 13 nM for S1R and 102 nM for S2R. This compound effectively reduces mechanical hypersensitivity, making it a valuable tool for research in pain mechanisms and neuropharmacology. Its application in studying the sigma receptor's role in various biological processes highlights its significance in addressing pain-related conditions and therapeutic interventions.
Chemical Information
| Catalog Num | A79279 |
|---|---|
| M. Wt | 384.94 |
| Formula | C23H29ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3026677-24-4 |
| Synonyms | |
| SMILES | O=C(N(CC1)CCC21CN(CCC3=CC=CC=C3)C2)CC4=CC=CC=C4.[H]Cl |
Biological Activity
| Description | AB21 hydrochloride is a potent and selective antagonist of the sigma-1 receptor (S1R), exhibiting a Ki of 13 nM for S1R and 102 nM for S2R. This compound effectively reduces mechanical hypersensitivity, making it a valuable tool for research in pain mechanisms and neuropharmacology. Its application in studying the sigma receptor's role in various biological processes highlights its significance in addressing pain-related conditions and therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
