Product Data Sheet

Sigma-1 receptor antagonist 6

Catalog No. A79298

main product photo
Sigma-1 receptor antagonist 6 is a selective antagonist of the Sigma-1 receptor (σ1R), exhibiting significant antiallodynic properties. This compound effectively reduces mechanical allodynia in neuropathic pain models, particularly in response to paclitaxel treatment. Its application in research settings enables the exploration of σ1R modulation in pain pathways and the development of novel analgesic therapies.
Chemical Information
Catalog NumA79298
M. Wt502.65
FormulaC32H34N6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1335032-28-4
Synonyms
SMILESC#CCN(C)C1=NC(NCCCC2CCN(CC3=CC=CC=C3)CC2)=C(C#N)C(C4=CC=CC=C4)=C1C#N
Biological Activity
DescriptionSigma-1 receptor antagonist 6 is a selective antagonist of the Sigma-1 receptor (σ1R), exhibiting significant antiallodynic properties. This compound effectively reduces mechanical allodynia in neuropathic pain models, particularly in response to paclitaxel treatment. Its application in research settings enables the exploration of σ1R modulation in pain pathways and the development of novel analgesic therapies.
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