Product Data Sheet

SAS-1121

Catalog No. A79307

main product photo
SAS-1121 is a selective ligand for the sigma 2 receptor and PGRMC1, exhibiting a Ki of 16.2 nM. It demonstrates a remarkable 574-fold selectivity for the sigma 2 receptor compared to the sigma 1 receptor. As a tertiary amine, SAS-1121 is valuable for studying mechanisms related to neurological conditions and offers potential insights into sigma receptor-related pathways in pharmacological research.
Chemical Information
Catalog NumA79307
M. Wt477.60
FormulaC28H35N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2095551-67-8
Synonyms
SMILESO=C(N1CC[C@]2([H])C3=CC=C(N4CCN(CCC(OCC)=O)CC4)C=C3[C@@]1([H])C2)OCC5=CC=CC=C5
Biological Activity
DescriptionSAS-1121 is a selective ligand for the sigma 2 receptor and PGRMC1, exhibiting a Ki of 16.2 nM. It demonstrates a remarkable 574-fold selectivity for the sigma 2 receptor compared to the sigma 1 receptor. As a tertiary amine, SAS-1121 is valuable for studying mechanisms related to neurological conditions and offers potential insights into sigma receptor-related pathways in pharmacological research.
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