Product Data Sheet
AB21
Catalog No. A79311
AB21 is a potent and selective antagonist of the sigma-1 receptor (S1R), exhibiting an IC50 value of 13 nM for S1R with minimal activity against the sigma-2 receptor (S2R) at 102 nM. This compound is effective in reducing mechanical hypersensitivity, making it a valuable tool for research into pain modulation and related neurological disorders. Additionally, AB21 may facilitate studies into the role of S1R in various physiological and pathological processes.
Chemical Information
| Catalog Num | A79311 |
|---|---|
| M. Wt | 348.48 |
| Formula | C23H28N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3026677-23-3 |
| Synonyms | |
| SMILES | O=C(N(CC1)CCC21CN(CCC3=CC=CC=C3)C2)CC4=CC=CC=C4 |
Biological Activity
| Description | AB21 is a potent and selective antagonist of the sigma-1 receptor (S1R), exhibiting an IC50 value of 13 nM for S1R with minimal activity against the sigma-2 receptor (S2R) at 102 nM. This compound is effective in reducing mechanical hypersensitivity, making it a valuable tool for research into pain modulation and related neurological disorders. Additionally, AB21 may facilitate studies into the role of S1R in various physiological and pathological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
