SW116 free base
Catalog No. A79317

SW116 free base is a selective fluorescent ligand for the sigma-2 receptor, exhibiting a binding affinity with a Ki value of 14 nM. This compound displays a maximal excitation wavelength of 333 nm and a maximal emission wavelength of 506 nm when dissolved in methanol. SW116 free base can be internalized by MDA-MB-435 cells, achieving 50% maximum fluorescent intensity within 24 minutes. Due to its properties, it serves as a valuable fluorescent probe in cancer research applications.
Chemical Information
| Catalog Num | A79317 |
|---|---|
| M. Wt | 692.95 |
| Formula | C39H56N4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1036759-00-8 |
| Synonyms | |
| SMILES | O=[S](NCCCCCCCCCCN([C@]1([H])C2)[C@@](CCC1)([H])C[C@@H]2OC(NC(C=C3C)=C(C=C3)OC)=O)(C4=CC=CC5=C4C=CC=C5N(C)C)=O |
Biological Activity
| Description | SW116 free base is a selective fluorescent ligand for the sigma-2 receptor, exhibiting a binding affinity with a Ki value of 14 nM. This compound displays a maximal excitation wavelength of 333 nm and a maximal emission wavelength of 506 nm when dissolved in methanol. SW116 free base can be internalized by MDA-MB-435 cells, achieving 50% maximum fluorescent intensity within 24 minutes. Due to its properties, it serves as a valuable fluorescent probe in cancer research applications. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


