Florzolotau
Catalog No. A79333

Florzolotau is a tau ligand designed for positron emission tomography (PET) imaging, targeting the β-sheet region of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein. Its binding affinity extends to intraneuronal inclusions present in Alzheimer's disease, primary age-related tauopathy, and posterior cortical atrophy. This compound shows significant potential in the diagnosis and study of tau proteinopathies, facilitating improved imaging of neurological disorders associated with tau aggregation.
Chemical Information
| Catalog Num | A79333 |
|---|---|
| M. Wt | 385.46 |
| Formula | C20H20FN3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1565797-16-1 |
| Synonyms | APN1607; PM-PBB3 |
| SMILES | OC(COC1=CC=C2N=C(/C=C/C=C/C3=CC=C(NC)N=C3)SC2=C1)CF |
Biological Activity
| Description | Florzolotau is a tau ligand designed for positron emission tomography (PET) imaging, targeting the β-sheet region of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein. Its binding affinity extends to intraneuronal inclusions present in Alzheimer's disease, primary age-related tauopathy, and posterior cortical atrophy. This compound shows significant potential in the diagnosis and study of tau proteinopathies, facilitating improved imaging of neurological disorders associated with tau aggregation. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


