Product Data Sheet

Florzolotau

Catalog No. A79333

main product photo
Florzolotau is a tau ligand designed for positron emission tomography (PET) imaging, targeting the β-sheet region of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein. Its binding affinity extends to intraneuronal inclusions present in Alzheimer's disease, primary age-related tauopathy, and posterior cortical atrophy. This compound shows significant potential in the diagnosis and study of tau proteinopathies, facilitating improved imaging of neurological disorders associated with tau aggregation.
Chemical Information
Catalog NumA79333
M. Wt385.46
FormulaC20H20FN3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1565797-16-1
SynonymsAPN1607; PM-PBB3
SMILESOC(COC1=CC=C2N=C(/C=C/C=C/C3=CC=C(NC)N=C3)SC2=C1)CF
Biological Activity
DescriptionFlorzolotau is a tau ligand designed for positron emission tomography (PET) imaging, targeting the β-sheet region of paired helical filaments (PHFs) and straight filaments (SFs) of tau protein. Its binding affinity extends to intraneuronal inclusions present in Alzheimer's disease, primary age-related tauopathy, and posterior cortical atrophy. This compound shows significant potential in the diagnosis and study of tau proteinopathies, facilitating improved imaging of neurological disorders associated with tau aggregation.
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SHIPPING AND STORAGE
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