Product Data Sheet
Tau ligand-1
Catalog No. A79337
Tau Ligand-1 is a specific ligand that targets aggregated tau protein and is capable of crossing the blood-brain barrier. Demonstrating high affinity for aggregated tau in brain tissues from Alzheimer's disease and other tauopathies, it displays equilibrium dissociation constant (KD) values between 1 and 3.8 nM. This compound shows potential as a positron emission tomography (PET) tracer, offering valuable applications in imaging studies related to tau-associated neurodegenerative diseases in the central nervous system.
Chemical Information
| Catalog Num | A79337 |
|---|---|
| M. Wt | 297.33 |
| Formula | C17H16FN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3063166-64-0 |
| Synonyms | |
| SMILES | FC1=NC(N2CCOCC2)=CC=C1C3=CC4=C(N3)C=CC=C4 |
Biological Activity
| Description | Tau Ligand-1 is a specific ligand that targets aggregated tau protein and is capable of crossing the blood-brain barrier. Demonstrating high affinity for aggregated tau in brain tissues from Alzheimer's disease and other tauopathies, it displays equilibrium dissociation constant (KD) values between 1 and 3.8 nM. This compound shows potential as a positron emission tomography (PET) tracer, offering valuable applications in imaging studies related to tau-associated neurodegenerative diseases in the central nervous system. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
