Product Data Sheet
BF-170
Catalog No. A79354
BF-170 is a selective tau fibril binding agent that targets tau protein aggregates, exhibiting an EC50 of 221 nM. It demonstrates effective blood-brain barrier permeability, with brain tissue concentrations reaching 9.1% ID/g within 2 minutes post intravenous administration in mice. BF-170 serves as a valuable tool for imaging tau pathology associated with Alzheimer's disease and is instrumental in early-stage AD research, offering potential for studies focused on tau-related neurodegenerative disorders.
Chemical Information
| Catalog Num | A79354 |
|---|---|
| M. Wt | 220.27 |
| Formula | C15H12N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 22191-97-5 |
| Synonyms | |
| SMILES | C1=CC=C2C(=C1)C=CC(=N2)C3=CC=C(C=C3)N |
Biological Activity
| Description | BF-170 is a selective tau fibril binding agent that targets tau protein aggregates, exhibiting an EC50 of 221 nM. It demonstrates effective blood-brain barrier permeability, with brain tissue concentrations reaching 9.1% ID/g within 2 minutes post intravenous administration in mice. BF-170 serves as a valuable tool for imaging tau pathology associated with Alzheimer's disease and is instrumental in early-stage AD research, offering potential for studies focused on tau-related neurodegenerative disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
