Product Data Sheet
JNJ-64326067
Catalog No. A79370
JNJ-64326067 is an aggregated tau protein binder with a Ki of 2.4 nM, demonstrating significant blood-brain barrier permeability. This compound selectively targets aggregated tau protein while exhibiting no binding affinity for aggregated β-amyloid or off-target interactions with various receptors, ion channels, transporters, kinases, and monoamine oxidases. JNJ-64326067 is a valuable tool for investigating the pathophysiology of Alzheimer's disease and exploring potential therapeutic strategies.
Chemical Information
| Catalog Num | A79370 |
|---|---|
| M. Wt | 253.28 |
| Formula | C15H12FN3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2173357-28-1 |
| Synonyms | |
| SMILES | FC1=CC(=NC=C1C)NC=2C=CC=3C=NC=CC3C2 |
Biological Activity
| Description | JNJ-64326067 is an aggregated tau protein binder with a Ki of 2.4 nM, demonstrating significant blood-brain barrier permeability. This compound selectively targets aggregated tau protein while exhibiting no binding affinity for aggregated β-amyloid or off-target interactions with various receptors, ion channels, transporters, kinases, and monoamine oxidases. JNJ-64326067 is a valuable tool for investigating the pathophysiology of Alzheimer's disease and exploring potential therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
