Product Data Sheet
Trk-IN-2
Catalog No. A79402
Trk-IN-2 is a potent pan-Trk kinase inhibitor, demonstrating an IC50 of 9 nM for the TrkA enzyme and a cell-based IC50 of 7 nM. This compound exhibits significant pharmacodynamic effects in rat models of inflammatory and neuropathic pain. Trk-IN-2 is valuable for research applications focused on the mechanisms and treatment of inflammatory pain and neuropathic pain conditions.
Chemical Information
| Catalog Num | A79402 |
|---|---|
| M. Wt | 468.53 |
| Formula | C24H24N10O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1614229-04-7 |
| Synonyms | |
| SMILES | O=C(NC1=CC(=NN1C=2C=NC=CC2)C(C)(C)C)CN3N=NC(=C3)C=4C=NC(=CC4)N5C=NC=C5 |
Biological Activity
| Description | Trk-IN-2 is a potent pan-Trk kinase inhibitor, demonstrating an IC50 of 9 nM for the TrkA enzyme and a cell-based IC50 of 7 nM. This compound exhibits significant pharmacodynamic effects in rat models of inflammatory and neuropathic pain. Trk-IN-2 is valuable for research applications focused on the mechanisms and treatment of inflammatory pain and neuropathic pain conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
