Product Data Sheet
PBT434 mesylate
Catalog No. A79410
PBT434 mesylate is an orally active α-synuclein aggregation inhibitor that effectively penetrates the blood-brain barrier. This compound functions as an iron chelator, modulating transcellular iron trafficking while inhibiting iron-mediated redox activity and the aggregation of α-synuclein. PBT434 mesylate demonstrates neuroprotective effects by preventing the loss of neurons in the substantia nigra pars compacta. It holds promise for advancing research in Parkinson’s disease.
Chemical Information
| Catalog Num | A79410 |
|---|---|
| M. Wt | 398.26 |
| Formula | C13H17Cl2N3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2387898-69-1 |
| Synonyms | ATH434 mesylate |
| SMILES | O=C1C2=C(N=C(CNCC)N1C)C(O)=C(Cl)C=C2Cl.O=S(O)(C)=O |
Biological Activity
| Description | PBT434 mesylate is an orally active α-synuclein aggregation inhibitor that effectively penetrates the blood-brain barrier. This compound functions as an iron chelator, modulating transcellular iron trafficking while inhibiting iron-mediated redox activity and the aggregation of α-synuclein. PBT434 mesylate demonstrates neuroprotective effects by preventing the loss of neurons in the substantia nigra pars compacta. It holds promise for advancing research in Parkinson’s disease. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
