Product Data Sheet
Tat-βsyn-degron
Catalog No. A79436
Tat-βsyn-degron is an α-synuclein knockdown peptide that promotes the degradation of α-synuclein through the proteasome pathway. This compound demonstrates significant efficacy in reducing α-synuclein protein levels in primary rat cortical neuron cultures. Additionally, Tat-βsyn-degron has shown potential in alleviating parkinsonian toxin-induced neuronal damage and movement disorders in a Parkinson's mouse toxicity model, making it a valuable tool for research into neurodegenerative diseases.
Chemical Information
| Catalog Num | A79436 |
|---|---|
| M. Wt | 3146.67 |
| Formula | C132H237N59O31 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2816095-52-8 |
| Synonyms | |
| SMILES | [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CC(C)C)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)CCCCN)=O)CO)=O)=O)C(C)C)=O |
Biological Activity
| Description | Tat-βsyn-degron is an α-synuclein knockdown peptide that promotes the degradation of α-synuclein through the proteasome pathway. This compound demonstrates significant efficacy in reducing α-synuclein protein levels in primary rat cortical neuron cultures. Additionally, Tat-βsyn-degron has shown potential in alleviating parkinsonian toxin-induced neuronal damage and movement disorders in a Parkinson's mouse toxicity model, making it a valuable tool for research into neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
