Product Data Sheet

α-Synuclein-IN-17

Catalog No. A79440

main product photo
α-Synuclein-IN-17 is a selective inhibitor of α-synuclein, demonstrating an IC50 value of 9 μM. This compound exhibits significant inhibitory activity against both in vitro assembled α-synuclein fibrils and those amplified from Lewy Body Disease brain tissue. α-Synuclein-IN-17 is a valuable tool for research into Parkinson's disease and Lewy Body Disease, aiding in the study of the pathophysiological mechanisms associated with these neurodegenerative conditions.
Chemical Information
Catalog NumA79440
M. Wt402.48
FormulaC22H30N2O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.676458-63-2
Synonyms
SMILESCOC1=CC(CN2CCN(CC3=CC(OC)=CC=C3OC)CC2)=CC(OC)=C1O
Biological Activity
Descriptionα-Synuclein-IN-17 is a selective inhibitor of α-synuclein, demonstrating an IC50 value of 9 μM. This compound exhibits significant inhibitory activity against both in vitro assembled α-synuclein fibrils and those amplified from Lewy Body Disease brain tissue. α-Synuclein-IN-17 is a valuable tool for research into Parkinson's disease and Lewy Body Disease, aiding in the study of the pathophysiological mechanisms associated with these neurodegenerative conditions.
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