Product Data Sheet
PQM-164
Catalog No. A79446
PQM-164 is an antioxidant agent that targets oxidative stress by exhibiting potent radical scavenging activity (IC50: 0.93 μM for DPPH radical). It demonstrates anti-inflammatory effects by mitigating neuronal damage induced by 6-OHDA in activated microglial cells, and it reduces α-synuclein accumulation. Additionally, PQM-164 promotes the nuclear translocation and transcriptional activity of Nrf2. This compound serves as a valuable tool for research into neurodegenerative conditions such as Parkinson’s disease.
Chemical Information
| Catalog Num | A79446 |
|---|---|
| M. Wt | 342.35 |
| Formula | C18H18N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2226535-25-5 |
| Synonyms | |
| SMILES | O=C(N/N=C/C1=CC=C(O)C(OC)=C1)/C=C/C2=CC=C(O)C(OC)=C2 |
Biological Activity
| Description | PQM-164 is an antioxidant agent that targets oxidative stress by exhibiting potent radical scavenging activity (IC50: 0.93 μM for DPPH radical). It demonstrates anti-inflammatory effects by mitigating neuronal damage induced by 6-OHDA in activated microglial cells, and it reduces α-synuclein accumulation. Additionally, PQM-164 promotes the nuclear translocation and transcriptional activity of Nrf2. This compound serves as a valuable tool for research into neurodegenerative conditions such as Parkinson’s disease. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
