Product Data Sheet
Keap1-Nrf2-IN-23
Catalog No. A79523
Keap1-Nrf2-IN-23 is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, exhibiting an IC50 of 16.0 nM. It demonstrates strong binding affinity to Keap1 with a Kd value of 3.07 nM, making it a valuable tool for research into antioxidant response pathways. This compound is suitable for studies related to cellular defense mechanisms and may have applications in the field of cancer research and neurodegenerative diseases.
Chemical Information
| Catalog Num | A79523 |
|---|---|
| M. Wt | 563.04 |
| Formula | C30H31ClN4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2771115-65-0 |
| Synonyms | |
| SMILES | O=C(N1CC2=CC=CC(C(CC(O)=O)C3=CC(OC)=C(N(C)N=N4)C4=C3)=C2CC1)C5=C(Cl)C=C(OC(C)C)C=C5 |
Biological Activity
| Description | Keap1-Nrf2-IN-23 is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, exhibiting an IC50 of 16.0 nM. It demonstrates strong binding affinity to Keap1 with a Kd value of 3.07 nM, making it a valuable tool for research into antioxidant response pathways. This compound is suitable for studies related to cellular defense mechanisms and may have applications in the field of cancer research and neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
